Predict the Active Enantiomer of
Chiral Agrochemicals
13 compound classes spanning herbicides, fungicides, and insecticides. 100% accuracy across 80 validated compounds with known active enantiomers. The same first-principles engine trusted for pharmaceutical chirality — now purpose-built for crop science.
Why Chirality Matters in Crop Protection
Over 30% of modern agrochemicals are chiral. The wrong enantiomer wastes material, increases environmental load, and can face regulatory barriers. Knowing the active form early in development saves years and millions in formulation costs.
Reduce Environmental Load
S-metolachlor uses 35% less active ingredient than racemic metolachlor with equal efficacy. Predicting the active enantiomer means lower application rates and reduced soil residues.
Accelerate Development
Get a chirality prediction in seconds instead of months of asymmetric synthesis and bioassay. Prioritize the right enantiomer from the first screen.
Meet Regulatory Demand
EPA and EU regulators increasingly require enantiomer-specific data for new registrations. ChiralCall provides confidence-scored predictions suitable for regulatory dossiers.
13 Agrochemical Compound Classes
Covering the major modes of action: ACCase inhibitors, ALS inhibitors, triazole DMIs, cyclopropane pyrethroids, ryanodine modulators, and more.
| Compound Class | Validated | Accuracy | Tier |
|---|---|---|---|
ACCase Herbicides Aryloxyphenoxy-propionates | 17 | 100% | T1 |
Triazole Fungicides (open-chain) Tertiary-carbinol, open-chain | 7 | 100% | T2 |
Triazole Fungicides (dioxolane) 1,3-dioxolane core | 7 | 100% | T2 |
Triazole Fungicides (fused ring) Fused ring / epoxide | 6 | 100% | T2 |
α-Carbon Triazole Fungicides No tertiary hydroxyl | 6 | 100% | T2 |
Pyrethroid Insecticides Cyclopropane 1R-active | 9 | 100% | T2 |
FOP Herbicides Aryloxyphenoxypropionic acid | 4 | 100% | T3 |
Chloroacetanilide Herbicides Metolachlor class | 4 | 100% | T3 |
Imidazolinone Herbicides ALS/AHAS inhibitors | 4 | 100% | T3 |
Metalaxyl-type Fungicides Methoxyacetyl acylalanine | 4 | 100% | T3 |
Benalaxyl-type Fungicides Phenylacetyl acylalanine | 4 | 100% | T3 |
Diamide Insecticides Ryanodine receptor | 4 | 100% | T3 |
Neonicotinoid Insecticides nAChR agonists | 4 | 100% | T3 |
T1 = Validated Production (N≥10, ≥90% accuracy, Wilson CI lower >80%) · T2 = Validated (N≥6, 100% accuracy, Wilson CI lower >54%) · T3 = below validation threshold
Built for Crop Science Workflows
Formulation R&D
When developing a new enantiopure formulation (like the switch from racemic metalaxyl to mefenoxam), ChiralCall predicts which enantiomer to target before committing to asymmetric synthesis. Submit a SMILES string, get an answer in seconds.
Patent & IP Strategy
Enantiomer switches (chiral switches) are a major IP strategy in agrochemistry. ChiralCall helps identify which enantiomer to claim in patent filings for new active ingredients before running the full bioassay panel.
Regulatory Submissions
EPA and EFSA increasingly require enantiomer-specific data. ChiralCall provides confidence-scored predictions with Wilson confidence intervals that can support regulatory dossiers as computational evidence alongside experimental data.
Batch API for Screening Libraries
Submit hundreds of compounds in one API call. Triage your screening library by predicted active enantiomer to focus synthesis resources on the right stereoisomers from the start.
Start Predicting Today
Free tier includes 5 predictions per month. Academic users with .edu emails get 100 predictions/month free — no credit card required.